Pythium Vaccine for the Treatment of Non-Resectable Oral Squamous Cell Carcinoma in Cats

Why are we doing this study?

Feline squamous cell carcinomas are one of the most difficult oral tumors to treat not just in veterinary oncology, but also in human oncology. Additional treatment options are always being investigated for use in this resistant tumor type. The use of an immune stimulating vaccine is being investigated for the effectiveness in feline oral squamous cell carcinoma. Pythium insidiosum is an infectious agent universal in distribution and is common in and near bodies of water. When Pythium extract is used for specific immunotherapy, an increase in the white blood cells responsible for identifying cancer cells is observed. In an early case series of squamous cell carcinomas in cows, regression of tumors were noted. Although this disease etiology is different in different species, side effects from the vaccine have not been observed and it is well tolerated. An injection is given under the skin once weekly.

How does my pet qualify?

If your cat has been diagnosed with an oral squamous cell carcinoma that is unable to be removed surgically, your pet may qualify. Your pet cannot currently be undergoing chemotherapy or radiation therapy at the time of the clinical study. Anti-inflammatories or prednisone is fine during the trial.

What are the benefits?

The cost of the vaccine is significantly reduced for use in patients enrolled in this clinical study. The costs of additional treatment for your pet’s mast cell tumor is not included as part of this study.

Who should I contact?

Please contact our staff for more information.